Hydrocodone/Acetaminophen

(Redirected from Norco)

General

  • Type: opioid (hydrocodone) + acetaminophen
  • Dosage Forms: PO
  • Common Trade Names: Norco

Adult Dosing

General

Pain:

  • 2.5-10mg hydrocodone/325mg Acetaminophen PO q4-6h

Pediatric Dosing

Not Currently recommended

Special Populations

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

  • Respiratory Depression
  • Apnea
  • syncope
  • bradycardia
  • Seizures
  • anaphylaxis
  • acetaminophen toxicity

Common

  • Nausea
  • Rash
  • Headache
  • Fatigue
  • xerostomia
  • constipation
  • Tremor
  • transaminitis

Pharmacology

  • Half-life: 4-5 hour
  • Metabolism: Liver
  • Excretion: urine
  • Mechanism of Action:binds to various opioid receptors
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