Nitrous oxide

(Redirected from Nitrous Oxide)


  • For minimal sedation or anxiolysis
  • It may be used as an adjunct with local anesthetics for more painful procedures



Nitrous accumulates in potential spaces and is potentially problematic when there are recent lung or ocular surgery.

Equipment Needed


  • Pre-sedation establishment of an IV is not required
  • General monitoring procedures shall be followed
  • Nitrous oxide administration should be limited to 30 minutes
  • Administer 100% oxygen for 2-5 minutes after discontinuing nitrous oxide or if nitrous oxide / oxygen administration is interrupted for > 30 seconds


See Nitrous oxide toxicity

  • Asphyxia, if oxygen is not given with the gas
    • Headache
    • Dizziness
    • Confusion
    • Syncope
    • Seizures
  • Chronic toxicity results from B12 inactivation
    • Megaloblastic anemia
    • Thrombocytopenia
    • Peripheral neuropathy

See Also

External Links