Methicillin-Sensitive Staphylococcus Aureus (MSSA)

Background

Antibiotic Sensitivities[1]

Category Antibiotic MSSA
Penicillins Penicillin G R
Penicillin V R
Methicillin S
Nafcillin/Oxacillin S
Cloxacillin/Diclox. S
Amino-Penicillins AMP/Amox R
Amox-Clav S
AMP-Sulb S
Anti-Pseudomonal Penicillins Ticarcillin R
Ticar-Clav S
Pip-Tazo S
Piperacillin R
Carbapenems Doripenem S
Ertapenem S
Imipenem S
Meropenem S
Aztreonam R
Fluroquinolones Ciprofloxacin S
Ofloxacin S
Pefloxacin S
Levofloxacin S
Moxifloxacin S
Gemifloxacin S
Gatifloxacin S
1st G Cephalo Cefazolin S
2nd G. Cephalo Cefotetan S
Cefoxitin S
Cefuroxime S
3rd/4th G. Cephalo Cefotaxime S
Cefizoxime S
CefTRIAXone S
Ceftaroline S
CefTAZidime I
Cefepime S
Oral 1st G. Cephalo Cefadroxil S
Cephalexin S
Oral 2nd G. Cephalo Cefaclor/Loracarbef S
Cefproxil S
Cefuroxime axetil S
Oral 3rd G. Cephalo Cefixime R
Ceftibuten R
Cefpodox/Cefdinir/Cefditoren S
Aminoglycosides Gentamicin S
Tobramycin S
Amikacin S
Chloramphenicol I
Clindamycin S
Macrolides Erythromycin I
Azithromycin S
Clarithromycin S
Ketolide Telithromycin S
Tetracyclines Doxycycline I
Minocycline S
Glycylcycline Tigecycline S
Daptomycin S
Glyco/Lipoclycopeptides Vancomycin S
Teicoplanin S
Telavancin S
Fusidic Acid S
Trimethoprim I
TMP-SMX S
Urinary Agents Nitrofurantoin S
Fosfomycin S
Other Rifampin S
Metronidazole R
Quinupristin dalfoppristin S
Linezolid S
Colistimethate R

Key

  • S susceptible/sensitive (usually)
  • I intermediate (variably susceptible/resistant)
  • R resistant (or not effective clinically)
  • S+ synergistic with cell wall antibiotics
  • U sensitive for UTI only (non systemic infection)
  • X1 no data
  • X2 active in vitro, but not used clinically
  • X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
  • X4 active in vitro, but not clinically effective for strep pneumonia

Table Overview

See Also

References

  1. Sanford Guide to Antimicrobial Therapy 2014

Authors:

Ross Donaldson