Medroxyprogesterone

Administration

  • Type:
  • Dosage Forms:
  • Routes of Administration:
  • Common Trade Names:

Adult Dosing

Non-pregnant vaginal bleeding

  • 20 mg PO TID for 7 days[1]
    • 76% success, median time 3 days
  • Alternative, not officially endorsed by ACOG: 150mg IM x 1 then 20 mg PO TID x 3 days
    • In a trial of 48 patients all had cessation in 5 days.[2]

Pediatric Dosing

Special Populations

Pregnancy Rating

Lactation risk

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

Comments

See Also

References

  1. Cite error: Invalid <ref> tag; no text was provided for refs named ACOG
  2. Ammerman SR, Nelson AL. A new progestogen-only medical therapy for outpatient management of acute, abnormal uterine bleeding: a pilot study. Am J Obstet Gynecol. 2013. 208(6):499.e1-e5.