Mebendazole

Administration

  • Type: Antiparasitic (used to treat nematodes)
  • Dosage Forms: Tablet 100mg
  • Routes of Administration: Oral
  • Common Trade Names: Emverm

Adult Dosing

  • 100mg PO BID x 3 days

Pediatric Dosing

≥2yo: 100mg PO BID x 3 days

Special Populations

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

  • Agranulocytosis
  • Hepatitis
  • Seizure
  • Angioedema

Common

  • Abdominal pain, diarrhea

Pharmacology

  • Half-life: 0.8-11.5h
  • Metabolism: Hepatic
  • Excretion: Fecal

Mechanism of Action

  • Causes parasitic microtubules to degenerate, inhibiting glucose uptake and glycogen storage

Comments

See Also

References

Authors:

Claire