Homatropine

Administration

Adult Dosing

  • 1-2 drops of 2% or 5% solution q3-4h

Pediatric Dosing

Safety/efficacy not established

Special Populations

  • Pregnancy Rating: Fetal risk has been demonstrated
  • Lactation risk: Infant risk cannot be ruled out
  • Renal dosing
  • Hepatic dosing

Contraindications

  • Allergy to class/drug
  • primary glaucoma or tendency toward glaucoma (e.g, narrow anterior chamber angle)

Adverse Reactions

Serious

  • Raised IOP
  • Keratitis
  • Systemic absorption and antimuscarinic reaction
  • Eye pain

Common

  • Burning sensation

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

  • Anticholinergic, blocks the responses of the sphincter muscle of the iris and stimulation of ciliary body muscle, leading to cycloplegia and mydriasis

Comments

See Also

References

Authors:

Claire