Homatropine
Administration
- Type: Anticholinergic, Cycloplegic
- Dosage Forms:
- Routes of Administration: Opthalmic
- Common Trade Names:
Adult Dosing
- 1-2 drops of 2% or 5% solution q3-4h
Pediatric Dosing
Safety/efficacy not established
Special Populations
- Pregnancy Rating: Fetal risk has been demonstrated
- Lactation risk: Infant risk cannot be ruled out
- Renal dosing
- Hepatic dosing
Contraindications
- Allergy to class/drug
- primary glaucoma or tendency toward glaucoma (e.g, narrow anterior chamber angle)
Adverse Reactions
Serious
- Raised IOP
- Keratitis
- Systemic absorption and antimuscarinic reaction
- Eye pain
Common
- Burning sensation
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Anticholinergic, blocks the responses of the sphincter muscle of the iris and stimulation of ciliary body muscle, leading to cycloplegia and mydriasis