|Plant-Based||Oxidized cellulose (OC) and oxidized regenerated cellulose (ORC)|
|Gelatin-based||Purified pork or bovine skin; absorbs 45 times its weight of its initial volume causing hemostasis. Excessive swelling can lead to nerve compression|
|Collagen-based||Derived from tissue; shows cell compatibility, adhesion, growth and migration.|
|Fibrin-based||High concentrations of fibrinogen, thrombin and additional components (clotting factors)|
|Thrombin-based||Directly participate in the coagulation cascade process that promotes and modulates coagulation. Provides a lattice for platelet aggregation and thrombus formation.|
|Chitin-based||Polysaccharide biopolymer produced naturally by algae through fermentation. Also known as chitosan in its deacetylated form. Chitosan has been shown to be more effective that chitin in controlling severe hemorrhage.|
|Charateristic||QuikClot ACS+||HemCon||Celox||WoundSat||Combat Gauze|
|Ready to use||Yes||Yes||Yes||Yes||Yes|
|2-year shelf life||Yes||Yes||Yes||Yes||Yes|
|Stable in extreme conditions||Yes||Yes||Yes||Yes||Yes|
|Cleared by FDA||Yes||Yes||Yes||Yes||Yes|
- For compressible hemorrhage not amenable to tourniquet use or as an adjunct to tourniquet removal (if evacuation time is anticipated to be longer than two hours), use Combat Gauze
- Celox Gauze and ChitoGauze may also be used if Combat Gauze is not available.
- Hemostatic dressings should be applied with at least 3 minutes of direct pressure.
- Kheirabadi B. "Evaluation of Topical Hemostatic Agents for Combat Wound Treatment." The Army Medical Department Journal. April – June 2011. Pages 25-31