Fentanyl

General

  • Type: Opiods
  • Dosage Forms: IV, intranasal, transdermal
  • Common Trade Names: Sublimaze

Adult Dosing

  • Analgesia: 1-2 mcg/kg IV/IM, q30-60 min PRN
  • Sedation: 1-3 mcg/kg/hr continuous infusion

Pediatric Dosing

0.5-2 mcg/kg IV q1-2 hr

Special Populations

  • Pregnancy Rating: C
  • Lactation: Excreted in breast milk, not recommended
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

  • Apnea

Common

  • Confusion
  • Constipation
  • Nausea/Vomiting
  • Somnolence
  • Sweating
  • Asthenia

Pharmacology

  • Half-life: 2-4 hours
  • Metabolism: Hepatic
  • Excretion: Renal
  • Mechanism of Action: Narcotic opiate receptor agonist

See Also

References

Micromedex