Doxylamine

Administration

  • Type:Antihistamine
  • Dosage Forms:
  • Routes of Administration: oral
  • Common Trade Names: Unisom

Adult Dosing

Pediatric Dosing

Not recommended for children <12 yo due to tendency to paradoxical reactions

  • 2-6yo: 1.9 to 3.125 mg q4-6h
  • 6-12 yo: 3.75 to 6.25 mg q4-6h

Special Populations

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

  • Somnolence

Pharmacology

  • Half-life: 10-18h
  • Metabolism: Hepatic - CYP450
  • Excretion: Urine

Mechanism of Action

  • H1-histamine blocker

Comments

See Also

References