Dextrose-based products
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Pediatric Hypoglycemia Dextrose Chart
| Category | Age | Glucose | Treatment | Initial IV Bolus | Maintenance Dose |
| Neonatal | <2mo | <40 | D10W | 2.5-5 mL/kg | 6 mL/kg/h |
| Pediatric | 2mo-8yrs | <60 | D25W | 2 mL/kg |
D10W:
|
| Adult | >8yrs | <70 | D50W | 50mL (1 amp) OR 1 mL/kg |
- Consider diluting the D25W or D50W bolus, with NS 1-to-1, as those concentrations may be sclerosing to veins
- Recheck 5 minutes after dose and repeat dose if low.
- Consider glucagon IM/SQ if IV access is not readily available
Dextrose Comparison
- D50W
- 25gm dextrose in 50mL sterile water (25g/50ml = 50% dextrose)
- D10W
- 25gm dextrose in 250mL sterile water (25gm/250mL = 10% dextrose)
- D5W
- 25gm dextrose in 500mL sterile water (25gm/500mL = 5% dextrose)
Rule of 50
Divide 50 by the type of dextrose solution to arrive at rate in ml/kg
- Adult (D50): 50/50 = 1 ml/kg
- Pediatric (D25): 50/25 = 2 ml/kg
- Infant (D10): 50/10 = 5 ml/kg
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Hypoglycemia | D50W 50 mL (25 g glucose) IV bolus | IV dextrose for AMS/unable to take PO | IV | Adult |
| Hypoglycemia | D25W 2-4 mL/kg IV; D10W 5 mL/kg IV (neonates) | IV dextrose (pediatric) | IV | Pediatric |
| Neonatal hypoglycemia | 2-3mL/kg of D10W IV bolus, then D10W infusion at 4-6mg/kg/min | Acute neonatal hypoglycemia | IV | Pediatric |
| Newborn resuscitation | 2-4mL/kg of D10W IV | Hypoglycemia | IV | Pediatric |
| Seizure (peds) | 2mL/kg of D25W | Hypoglycemic seizure (glucose <50mg/dL) | IV | Pediatric |
| Status epilepticus (peds) | D25W 2mL/kg (max 100mL) or D10W 5mL/kg (max 250mL) | If blood glucose <60mg/dL | IV | Pediatric |