Cyclopentolate

Administration

  • Type: Cycloplegic, topical anticholinergics
  • Dosage Forms:
  • Routes of Administration: Ophthalmic
  • Common Trade Names: Cyclogyl, Cylate, Pentolair

Adult Dosing

  • 1-2 drops of 0.5%-2% solution, may repeat in 5-10min if needed

Pediatric Dosing

  • Small infants: 1 drop of 0.5%-2% solution
  • Children: 1-2 drops of 0.5%-2% solution, may repeat with 0.5%-1% solution in 5-10min if needed

Special Populations

  • Pregnancy Rating: C
  • Lactation risk: infant risk cannot be ruled out
  • Renal dosing
  • Hepatic dosing

Contraindications

  • Allergy to class/drug
  • Narrow-angle glaucoma or anatomically narrow angles

Adverse Reactions

Serious

  • Tachyarrythmia, vasodilation
  • Seizure
  • Ataxia, confusion, psychosis
  • Conjunctivitis
  • Raised intraocular pressure

Common

  • Blurred vision
  • Burning sensation in eye
  • Photophobia

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

  • Anticholinergic, blocks the responses of the sphincter muscle of the iris and stimulation of ciliary body muscle, leading to cycloplegia and mydriasis.

Comments

See Also

References

Authors:

Claire