Bisacodyl

Administration

  • Type: laxative
  • Dosage Forms: tablet, enema, suppository
  • Dosage Strengths: tablet: 5mg; enema: 10mg/30mL; suppository: 10mg
  • Routes of Administration: PO, PR
  • Common Trade Names: Dulcolax, Correctol, BisacEvac, Bisacolax, Codulax, Alophen, Feen A Mint, Fleet Stimulant Laxative, Laxit, Modane

Adult Dosing

  • 5-30mg PO daily
  • 10mg suppository daily

Pediatric Dosing

  • 6-11 yrs: 5mg or rectally daily

Special Populations

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug
  • Appendicitis
  • Bowel obstruction
  • Gastroenteritis

Adverse Reactions

Serious

  • Colonic atony

Common

  • Abdominal discomfort/colic, diarrhea, proctitis (with suppository use)

Pharmacology

  • Half-life: 8 hr
  • Metabolism: Metabolized to BHPM in the colon
  • Excretion: Urine and bile

Mechanism of Action

  • Stimulates peristalsis via parasympathetic reflexes

Comments

See Also

References