Acne vulgaris
Background
- Acne vulgaris is a chronic inflammatory skin condition affecting pilosebaceous units
- Most common skin condition in adolescents and young adults
- Pathogenesis involves follicular hyperkeratinization, increased sebum production, Cutibacterium acnes colonization, and inflammation
Clinical Features
- Open and closed comedones
- Inflammatory papules and pustules
- Nodules and cysts in severe cases
- Distribution: face, chest, back, shoulders
Differential Diagnosis
Acneiform rash
- Rosacea
- Folliculitis
- Drug-induced acne
Evaluation
- Clinical diagnosis based on morphology and distribution
- Grade severity: mild (comedonal), moderate (papulopustular), severe (nodulocystic)
Management
Antibiotic Dosing
Adult
- Doxycycline 100mg PO daily
Pediatric
- Doxycycline >8 years old: weight <45kg: 2.2mg/kg/dose PO QD-BID; weight >45kg: adult dosing
Disposition
- Outpatient management with dermatology follow-up
- Refer to dermatology for severe or refractory cases