Measles: Difference between revisions

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*10d incubation period
*10d incubation period
*3d prodromal period
*3d prodromal period
===Current Outbreaks===
*2/14
**14 known measles cases in California
**5 of the patients recently traveled to the Philippines or had contact with international travelers
**the majority of patients were unvaccinated
**a recent outbreak in the Philippines has resulted in over 20 deaths and thousands of cases


==Diagnosis==
==Diagnosis==
*URI symptoms: high fever, cough, conjunctivitis, coryza
*Begins with URI symptoms: high fever, cough, coryza, and conjunctivitis
*Rash
*Koplik's spots may appear in 2-3 days after onset of symptoms
**Begins 4 days after onset of symptoms
**Pathognomonic enanthem
**Spreads from central to peripheral
**Tiny red spots (base) with bluish-white centers on the mucosa of the cheek or palate
**Initially is erythematous and maculopapular; rapidly progresses to confluence (face)
*Then rash (begins day 4 - lasts to day 7)
**Lasts 7d
**red, blotchy, and maculopapular; rapidly progresses to confluence
**Koplik spots
**Usually starts on the face (hairline and behind the ears)
***Pathognomonic enanthem
**Rapidly spreads to the chest, back, and finally the legs and feet
***White to bluish-white lesions w/ red base on buccal mucosa
*Obtain a history of measles immunization, travel outside of the Americas, or contact with international travelers in recent weeks.  Simple community transmission is also possible.
 
==Work Up==
*Usually you need (check with your lab):
**1-2 ml blood in a red-top tube
**throat or nasopharyngeal swab using a viral culturette with viral transport media
**10-40 ml of urine in a sterile container.
 
==Management==
*ALERT YOUR LOCAL HEALTH DEPARTMENT ASAP
**The risk of measles transmission to others and large contact investigations can be reduced if control measures are implemented immediately.
 
===Post-Exposure Prophylaxis===
*Can be administered to contacts
*Checking with your local health authorities
**Within 72 hours of exposure use MMR vaccine
**Up to 6 days after exposure use IM immune globulin
 
===Infectious Precautions===
*For suspected patients
**MASK the patient and ISOLATE immediately in an airborne infection isolation room
**All personnel entering the room should use respiratory protection at least as effective as an N95 respirator
**If possible, allow only personnel with documentation of 2 doses of live measles vaccine or laboratory evidence of immunity (measles IgG positive) to enter the room
**Do not use the room for at least 2 hours after the patient leaves.


==See Also==
==See Also==
[[Rashes (Peds)]]
[[Rashes (Peds)]]
==Source==
*VEP HEALTH ADVISORY 2/25/14


[[Category:ID]]
[[Category:ID]]
[[Category:Derm]]
[[Category:Derm]]
[[Category:Peds]]
[[Category:Peds]]

Revision as of 01:58, 26 February 2014

Background

  • 10d incubation period
  • 3d prodromal period

Current Outbreaks

  • 2/14
    • 14 known measles cases in California
    • 5 of the patients recently traveled to the Philippines or had contact with international travelers
    • the majority of patients were unvaccinated
    • a recent outbreak in the Philippines has resulted in over 20 deaths and thousands of cases

Diagnosis

  • Begins with URI symptoms: high fever, cough, coryza, and conjunctivitis
  • Koplik's spots may appear in 2-3 days after onset of symptoms
    • Pathognomonic enanthem
    • Tiny red spots (base) with bluish-white centers on the mucosa of the cheek or palate
  • Then rash (begins day 4 - lasts to day 7)
    • red, blotchy, and maculopapular; rapidly progresses to confluence
    • Usually starts on the face (hairline and behind the ears)
    • Rapidly spreads to the chest, back, and finally the legs and feet
  • Obtain a history of measles immunization, travel outside of the Americas, or contact with international travelers in recent weeks. Simple community transmission is also possible.

Work Up

  • Usually you need (check with your lab):
    • 1-2 ml blood in a red-top tube
    • throat or nasopharyngeal swab using a viral culturette with viral transport media
    • 10-40 ml of urine in a sterile container.

Management

  • ALERT YOUR LOCAL HEALTH DEPARTMENT ASAP
    • The risk of measles transmission to others and large contact investigations can be reduced if control measures are implemented immediately.

Post-Exposure Prophylaxis

  • Can be administered to contacts
  • Checking with your local health authorities
    • Within 72 hours of exposure use MMR vaccine
    • Up to 6 days after exposure use IM immune globulin

Infectious Precautions

  • For suspected patients
    • MASK the patient and ISOLATE immediately in an airborne infection isolation room
    • All personnel entering the room should use respiratory protection at least as effective as an N95 respirator
    • If possible, allow only personnel with documentation of 2 doses of live measles vaccine or laboratory evidence of immunity (measles IgG positive) to enter the room
    • Do not use the room for at least 2 hours after the patient leaves.

See Also

Rashes (Peds)

Source

  • VEP HEALTH ADVISORY 2/25/14