Ibutilide: Difference between revisions
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Revision as of 21:45, 18 November 2011
Adult Dosing
- Loading dose = 1mg IV in 50mL D5W over 10min (wt>60kg)
- Loading dose = 0.01mg/kg IV in 50mL D5W over 10min (wt<60kg)
- Dose may be repeated 10min after completion of 1st dose
Contraindications
Indications
- Rapid conversion of recent-onset A-fib/flutter to NSR
Mechanism of Action
- Class III - Prolongs AP and refractory period
Adverse Drug Rxns
- QT prolongation, V-tach, torsades
- Observe for 4hr after infusion
Kinetics
- Onset of action = 20-30min
- Duration of action = 24hr