Ibutilide: Difference between revisions
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== Adult Dosing == | ==General== | ||
*Type: [[Antiarrhythmics]] | |||
*Dosage Forms: | |||
*Common Trade Names: | |||
==Adult Dosing== | |||
*Loading dose = 1mg IV in 50mL D5W over 10min (wt>60kg) | *Loading dose = 1mg IV in 50mL D5W over 10min (wt>60kg) | ||
*Loading dose = 0.01mg/kg IV in 50mL D5W over 10min (wt<60kg) | *Loading dose = 0.01mg/kg IV in 50mL D5W over 10min (wt<60kg) | ||
*Dose may be repeated 10min after completion of 1st dose | *Dose may be repeated 10min after completion of 1st dose | ||
== | ==Pediatric Dosing== | ||
==Special Populations== | |||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | |||
*[[Lactation risk categories|Lactation risk]]: | |||
*Renal Dosing | |||
**Adult | |||
**Pediatric | |||
*Hepatic Dosing | |||
**Adult | |||
**Pediatric | |||
== Indications == | == Indications == | ||
*Rapid conversion of recent-onset A-fib/flutter to NSR | *Rapid conversion of recent-onset A-fib/flutter to NSR | ||
== | ==Contraindications== | ||
* | *Allergy to class/drug | ||
== Adverse | ==Adverse Reactions== | ||
*QT prolongation, V-tach, torsades | *QT prolongation, V-tach, torsades | ||
*Observe for 4hr after infusion | *Observe for 4hr after infusion | ||
== Kinetics == | ==Pharmacology== | ||
*Half-life: | |||
*Metabolism: | |||
*Excretion: | |||
*Mechanism of Action: Class III - Prolongs AP and refractory period | |||
=== Kinetics === | |||
*Onset of action = 20-30min | *Onset of action = 20-30min | ||
*Duration of action = 24hr | *Duration of action = 24hr | ||
==Comments== | |||
==See Also== | ==See Also== | ||
[[Antiarrhythmics]] | *[[Antiarrhythmics]] | ||
==References== | |||
<references/> | |||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 14:29, 1 June 2015
General
- Type: Antiarrhythmics
- Dosage Forms:
- Common Trade Names:
Adult Dosing
- Loading dose = 1mg IV in 50mL D5W over 10min (wt>60kg)
- Loading dose = 0.01mg/kg IV in 50mL D5W over 10min (wt<60kg)
- Dose may be repeated 10min after completion of 1st dose
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation risk:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Indications
- Rapid conversion of recent-onset A-fib/flutter to NSR
Contraindications
- Allergy to class/drug
Adverse Reactions
- QT prolongation, V-tach, torsades
- Observe for 4hr after infusion
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: Class III - Prolongs AP and refractory period
Kinetics
- Onset of action = 20-30min
- Duration of action = 24hr