Enoxaparin: Difference between revisions
Ostermayer (talk | contribs) (Text replacement - "Category:Drugs" to "Category:Pharmacology") |
|||
| Line 32: | Line 32: | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
*Bleeding | |||
**Treatment = Protamine | |||
***Does not completely reverse LMWHs | |||
***Carries significant anaphylaxis risk (0.2%); only use for major bleeding | |||
***Protamine 1mg IV for every 1mg of enoxaparin given in previous 8h | |||
****If 8–12h since last enoxaparin dose give 0.5mg IV for every 1mg of enoxaparin given | |||
*Pruritus | |||
*Local skin reaction | |||
==Pharmacology== | ==Pharmacology== | ||
Revision as of 13:34, 3 April 2016
General
- Type: Low molecular weight heparin
- Dosage Forms:
- Common Trade Names: Lovenox
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Renal impairment (Cr clearance <30)
- Use 50% of usual dose or use UFH instead
- Adult
- Pediatric
- Renal impairment (Cr clearance <30)
- Hepatic Dosing
- Adult
- Pediatric
- Obesity
- Weight-based dosing safe up to 190kg (no data available thereafter)
Indications
Contraindications
- Allergy to class/drug
Adverse Reactions
- Bleeding
- Treatment = Protamine
- Does not completely reverse LMWHs
- Carries significant anaphylaxis risk (0.2%); only use for major bleeding
- Protamine 1mg IV for every 1mg of enoxaparin given in previous 8h
- If 8–12h since last enoxaparin dose give 0.5mg IV for every 1mg of enoxaparin given
- Treatment = Protamine
- Pruritus
- Local skin reaction
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: