Glomerulonephritis

Background

• Characterized by hematuria and proteinuria

Diagnosis

• History
  • Recent URI or skin infection (strep)
  • Rash, arthralgia (HSP, SLE)
  • Fever, vomiting, diarrhea (HUS)
• Often a/w HTN

DDx

• Etiology
  • Poststreptococcal glomerulonephritis
  • Hemolytic-uremic syndrome
  • Henoch-Schonlein purpura
  • IgA nephropathy
  • Lupus
  • Alport syndrome

Work-Up

• UA
  • Hematuria, proteinuria, RBC casts
• CBC
• Chemistry
• Albumin (often reduced in acute glomerulonephritis)
• C3, C4, ASO

Treatment

Defer to nephrologist

Disposition

Coordinate with nephrologist

Source

Tintinalli