PERC rule

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Pulmonary Embolism Rule Out (PERC) Criteria

If all BREATHS are present AND low suspicion for PE, no D-dimer needed:

  • B- No blood in sputum
  • R- Room air sat > 95%
  • E- No estrogen or hormone use
  • A- Age < 50
  • T- No prior DVT or PE
  • H- Heart rate < 100bpm
  • S- No surgery/trauma requiring hospitalization in past 4 weeks
  • Note: Inclusion Criteria
    • Use this criteria if confident in excluding PE with negative D-dimer


  • Validated on 7527 patients
    • Only 0.9% had PE when PERC -, no deaths
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