Template:Nicotine Clinical Features

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Postive Negative
Anxiolysis Gastrointestinal Distress
Congnitive Enhancement Hypothermia
Cerebrovasodilation Emesis
Neuroprotection Hypertension
Analgesia Seizures
Antipscyhotic Respiratory Distress

Eye Pain

  • Nicotine is also an irritant and eye pain is a frequent complaint

Fasciculations

  • Due to the neuromuscular nicotinic activation

Hypersalivation

At high doses nicotine will activate muscarinic receptors

Biphasic presentation

  • Initially present with excitation, N/V/D, salivation, tachycardia, hypertension, diaphoresis
  • Delayed presentation is hypotension, bradycardia, hypoventilation, fasiculations, seizures, coma, and death
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