Homatropine

Administration

• Type: Anticholinergic, Cycloplegic
• Dosage Forms:
• Routes of Administration: Opthalmic
• Common Trade Names:

Adult Dosing

• 1-2 drops of 2% or 5% solution q3-4h

Pediatric Dosing

Safety/efficacy not established

Special Populations

• Pregnancy Rating: Fetal risk has been demonstrated
• Lactation risk: Infant risk cannot be ruled out
• Renal dosing
• Hepatic dosing

Contraindications

• Allergy to class/drug
• primary glaucoma or tendency toward glaucoma (e.g, narrow anterior chamber angle)

Adverse Reactions

Serious

• Raised IOP
• Keratitis
• Systemic absorption and antimuscarinic reaction
• Eye pain

Common

• Burning sensation

Pharmacology

• Half-life:
• Metabolism:
• Excretion:

Mechanism of Action

• Anticholinergic, blocks the responses of the sphincter muscle of the iris and stimulation of ciliary body muscle, leading to cycloplegia and mydriasis

See Also

• Cycloplegic