Hemostatic agents
Revision as of 07:46, 12 January 2016 by Rossdonaldson1 (talk | contribs)
Active Agents
| Plant-Based | Oxidized cellulose (OC) and oxidized regenerated cellulose (ORC) |
| Gelatin-based | Purified pork or bovine skin; absorbs 45 times its weight of its initial volume causing hemostasis. Excessive swelling can lead to nerve compression |
| Collagen-based | Derived from tissue; shows cell compatibility, adhesion, growth and migration. |
| Fibrin-based | High concentrations of fibrinogen, thrombin and additional components (clotting factors) |
| Thrombin-based | Directly participate in the coagulation cascade process that promotes and modulates coagulation. Provides a lattice for platelet aggregation and thrombus formation. |
| Chitin-based | Polysaccharide biopolymer produced naturally by algae through fermentation. Also known as chitosan in its deacetylated form. Chitosan has been shown to be more effective that chitin in controlling severe hemorrhage. |
Types
Use
- For compressible hemorrhage not amenable to tourniquet use or as an adjunct to tourniquet removal (if evacuation time is anticipated to be longer than two hours), use Combat Gauze
- Celox Gauze and ChitoGauze may also be used if Combat Gauze is not available.
- Hemostatic dressings should be applied with at least 3 minutes of direct pressure.