Thyroid disease (main)

Background

• Spectrum of Disease
  • Myxedema coma << hypothyroid < euthyroid > hyperthyroid >> thyroid storm

Other

1. Cretinism - no congenital t3/t4
2. Parafollicular C cells make calcitonin to keep the bone in
3. Endemic goiter- if pt from area c low iodine I intake
4. Free t3 & t4 determines thyroid state - not total plasma conc
5. T4-> T3 active & rt3 inactive
6. TRH -> TSH -> T4 -> T3

Thyroid Studies and Etiologies

• Hyperthyroidism
• Subclinical hyperthyroidism
• T3 toxicosis
• Thyroiditis, T4 ingestion, hyperthyroidism of elderly or cormorbid illness
• Euthyroid sick syndrome, central hypothyroidism
• Subclinical hypothyroidism, recovery from euthyroid sick syndrome
• Primary hypothyroidism
• TSH producing pituitary adenoma

See Also

• Thyroid Storm
• Hyperthyroidism
• Myxedema Coma
• Hypothyroidism