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Fluoroquinolones

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Indications

Adverse Effects

Black box warning from US FDA

Tendon Rupture & Tendinitis ^[1]
Peripheral Neuropathy^[2]

Clinically Utilized Antibiotics

Natural	Penicillin G Penicillin V

Anti-Staphylococcal	Cloxacillin Dicloxacillin Oxacillin Nafcillin

Amino-Penicillins	Amoxicillin Ampicillin Amoxicillin/Clavulanate Ampicillin/Sulbactam

Anti-Pseudomonal	Piperacillin/Tazobactam Ticarcillin/Clavulanate

Imipenem/Cilastin

1st	Cefazolin (Ancef) Cefadroxil Cephalexin (Keflex)

2nd	Cefuroxime Cefoxitin Cefotetan Cefaclor Cefprozil

3rd	Cefdinir Cefixime Cefotaxime Cefpodoxime Ceftriaxone Ceftazidime Cefditoren Ceftibuten

4th (antipseudomonal)	Cefepime

5th	Ceftaroline fosamil (Teflaro)

Monobactams

Aminoglycosides

-mycin (Streptomyces)	Streptomycin Neomycin Kanamycin Amikacin Tobramycin Spectinomycin Paromomycin

-micin (Micromonospora)	Gentamicin

Tetracyclines	Doxycycline Minocycline Tetracycline

Glycylcyclines	Tigecycline

Standard	Azithromycin Clarithromycin Erythromycin

Ketolide	Telithromycin

TMP-SMX (Bactrim)

Urinary Tract Agents

Fluroquinolones

2nd g.	Ciprofloxacin Ofloxacin

3rd g.	Levofloxacin

4th g.	Gemifloxacin Moxifloxacin Gatifloxacin

Other

Chloramphenicol

Quinupristin/dalfopristin

See Also

Antibiotics (Main)

References

↑ Gültuna S. et al. Ciprofloxacin induced tendinitis. J Clin Rheumatol. 2009;15 (4): 201-2
↑ Food and Drug Administration: Drug safety announcement about fluoroquinolones and possible peripheral neuropathy PDF

Goodman & Gilman's Pharmacology
FDA info for Health Professionals

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