Peritonsillar abscess
Background
- Abbreviation: PTA
- Most common deep head and neck infection in all populations
- Generally preceded by pharyngitis, tonsillitis, or peritonsillar cellulitis
- Abscess between tonsillar capsule and superior constrictor and palatopharyngeus muscles
- Location affected: superior > middle > inferior pole of tonsil
- Variable presentation, may range from minimal sore throat to sepsis and airway obstruction
- Microbiology
- Polymicrobial: strep/staph, anaerobes, eikenella, haemophilus influenzae, Fusobacterium necrophorum
Clinical Features
Symptoms
- Sore throat
- Fever, chills
- Odynophagia/dysphagia
- May have neck or ear pain
Signs
- Trismus, drooling, or saliva pooling
- Muffled voice ("hot potato voice")
- Peritonsillar edema/fluctuance and contralateral deflection of swollen uvula
- Cervical lymphadenopathy
Differential Diagnosis
Acute Sore Throat
Bacterial infections
- Streptococcal pharyngitis (Strep Throat)
- Neisseria gonorrhoeae
- Diphtheria (C. diptheriae)
- Bacterial Tracheitis
Viral infections
- Infectious mononucleosis (EBV)
- Patients with peritonsillar abscess have a 20% incidence of mononucleosis [1]
- Laryngitis
- Acute Bronchitis
- Rhinovirus
- Coronavirus
- Adenovirus
- Herpesvirus
- Influenza virus
- Coxsackie virus
- HIV (Acute Retroviral Syndrome)
Noninfectious
Other
- Deep neck space infection
- Peritonsillar Abscess (PTA)
- Epiglottitis
- Kawasaki disease
- Penetrating injury
- Caustic ingestion
- Lemierre's syndrome
- Peritonsillar cellulitis
- Lymphoma
- Internal carotid artery aneurysm
- Oral Thrush
- Parotitis
- Post-tonsillectomy hemorrhage
- Vincent's angina
- Acute necrotizing ulcerative gingivitis
Dentoalveolar Injuries
Odontogenic Infections
- Acute alveolar osteitis (dry socket)
- Acute necrotizing ulcerative gingivitis (trench mouth)
- Dental abscess
- Periapical abscess
- Periodontal abscess
- Ludwig's angina
- Pulpitis (dental caries)
- Pericoronitis
- Peritonsillar abscess (PTA)
- Retropharyngeal abscess
- Vincent's angina - tonsillitis and pharyngitis
Other
Evaluation
Endocavitary probe shows hypoechoic circumscribed area consistent with abscess[2]
- Primarily a clinical diagnosis, though diagnostic uncertainty and assessment of the size/nature requires imaging
- Labs
- CBC
- CMP
- Blood cultures or culture/sensitivity of abscess fluid
- Ultrasound
- Differentiates cellulitis from abscess
- Can use an intraoral approach using a endocavitary probe or transcutaneous approach using a linear probe
- Can identify depth of neck vasculature prior to aspiration
- May be limited by trismus, gag reflex, and operator technique
- CT with IV contrast
- Appears as ring-enhancing hypodense mass
- Differentiates PTA from parapharyngeal or retropharyngeal space infection
Management
Drainage
- The recurrence rate after aspiration is 10% and the cure rate is 93% to 95%. Recurrence rate for aspiration alone may be higher than I&D [3][4]
- May need IV pain meds, sedation or procedural sedation
- Glycopyrrolate can reduce secretions
Needle Aspiration
- Apply anesthetic spray to overlying mucosa
- Have patient hold suction and use as needed
- Use laryngoscope or disassembled vaginal speculum with wand as tongue depressor and light source
- Inject 1-2mL of lidocaine with epinephrine into mucosa of anterior tonsillar pillar using 25 gauge needle
- Cut distal tip off of needle sheath and place over 18ga needle to expose 1 cm of needle to prevent accidentally plunging deeper than desired
- Aspirate using 18 gauge needle just lateral to the tonsil
- Use static ultrasound to determine depth of vasculature.
- Though always a concern, carotid injury has not been clearly documented as a complications[5]
- May require multiple aspirations to find the abscess
- First try superior then middle then inferior poles
- Consider spinal needle if patient has significant trismus
I&D
- #11 or #15 blade scalpel
- Do not penetrate more than 1cm
- Only advance posteriorly
- May be indicated if significant pus with needle aspiration
- Macintosh size 3 or 4 with handle in a "tomahawk" position provides visualization with lighting[6]
Antibiotics Alone
Caution: No prospective, controlled studies are currently available to support this approach as of 2020. Systematic Review and Meta Analysis was attempted in 2020 which included the other citations from this post and found only low-quality data[7]
- The medications below and ED observation for 1-2 hours after, with liquid PO challenge:
- D5-1/2 NS, 1 L bolus
- IV NSAIDs, antipyretics
- Dexamethasone 10 mg IV
- Ceftriaxone 2 g IV, Ampicillin/Sulbactam 3 g IV, or Clindamycin 600 mg IV
- Upon discharge, Clindamycin 300 mg PO QID x10-14 days vs Amoxicillin/Clavulanate 875mg PO BID x10-14 days
- Pediatric protocol is the same, with weight based dosing
Antibiotics
Coverage for Streptococcus species, anerobes, Eikenella, H. influenza, S. auresus
Outpatient Options
- Clindamycin 300mg PO Q6hrs x7-10d
- Amoxicillin/Clavulanate 875 mg PO BID x 7-10d
- Penicillin V 500mg PO + Metronidazole 500mg QID
Inpatient Options
- Ampicillin/Sulbactam 3 gm (75mg/kg) IV four times daily
- Pipericillin/Tazobactam 4.5 gm IV TID
- Ticarcillin/Clavulanate 3.1 g IV QID
- Clindamycin 600-900mg IV TID
- Penicillin G 4 million units (50,000 units/kg) IV four times daily + Metronidazole 500mg IV three times daily
Steroids
Decreases duration and severity of pain[8]
- Methylprednisolone 125mg IV x1 OR dexamethasone 10mg PO/IM x1
Disposition
- Generally may be discharged with ENT follow-up and PO antibiotics
- Weight PO tolerance, probability of follow-up failure, antibiotics adherence in deciding disposition
- If no pus can be obtained but there is high suspicion for a PTA, admit with IV antibiotics (30% neg aspiration still have PTA)
- In pediatric patients 50% respond to med management[9]
Return Precautions
- shortness of breath
- Worsening throat or neck pain
- Enlarging mass
- Bleeding
- Neck stiffness
Prognosis
Complications
- Airway obstruction
- Rupture abscess with aspiration of contents
- Hemorrhage due to erosion of carotid sheath
- Retropharyngeal abscess
- Mediastinitis
- Recurrence occurs in 10-15% of patients
- Lemierre's syndrome
- Iatrogenic laceration of carotid artery
- Carotid artery is 2.5 cm posterior and lateral to tonsil
- Should limit depth of needle insertion to <10mm during aspiration
Indications for tonsillectomy
- Airway obstruction
- Recurrent severe pharyngitis or PTA
- Failure of abscess resolution with drainage
See Also
External Links
References
- ↑ Melio, Frantz, and Laurel Berge. “Upper Respiratory Tract Infection.” In Rosen’s Emergency Medicine., 8th ed. Vol. 1, n.d.
- ↑ http://www.thepocusatlas.com/soft-tissue-vascular/
- ↑ Johnson RF, Stewart MG. The contemporary approach to diagnosis and man- agement of peritonsillar abscess. Curr Opin Otolaryngol Head Neck Surg. 2005;13:157
- ↑ Wolf M. Peritonsillar abscess: repeated needle aspiration versus incision and drainage. Ann Otol Rhinol Laryngol. 1994 Jul;103(7):554-7.
- ↑ Herzon FS, Martin AD. Medical and surgical treatment of peritonsillar, retropharyngeal, and parapharyngeal abscesses. Curr Infect Dis Rep. 2006;8(3):196.
- ↑ Ballew JD. Unlocking Common ED Procedures – Peritonsillar Abscess Drainage. Arp 4, 2019. http://www.emdocs.net/unlocking-common-ed-procedures-peritonsillar-abscess-drainage/.
- ↑ 12. Medical Intervention Alone vs Surgical Drainage for Treatment of Peritonsillar Abscess: A Systematic Review and Meta-analysis. Forner D., et al, Otolaryngology–Head and Neck Surgery 2020, Vol. 163(5) 915–922
- ↑ Hur, K., Zhou, S., & Kysh, L. (2018). Adjunct steroids in the treatment of peritonsillar abscess: A systematic review. The Laryngoscope, 128(1), 72–77. https://doi.org/10.1002/lary.26672
- ↑ Blotter JW, Yin L, Glynn M, et al. Otolaryngology consultation for peritonsillar abscess in the pediatric population. Laryngoscope. 2000;110(10 Patient 1):1698.
