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Overdose symptoms by system

System	Minor or moderate overdose	Severe overdose
Cardiovascular	Cardiac dysrhythmia Hypertension or hypotension	Cardiogenic shock Cerebral hemorrhage Circulatory collapse
Central nervous system	Confusion Hyperreflexia Severe agitation Tremor	Acute amphetamine psychosis (e.g., delusions and paranoia) Compulsive and repetitive movement Serotonin syndrome Sympathomimetic toxidrome
Musculoskeletal	Myalgia	Rhabdomyolysis
Respiratory	Rapid breathing	Pulmonary edema Pulmonary hypertension Respiratory alkalosis
Urinary	Dysuria Urinary retention	Anuria Kidney failure
Other	Hyperthermia Mydriasis	Hyperkalemia or hypokalemia Hyperpyrexia Metabolic acidosis