Lithium: Difference between revisions

Revision as of 03:24, 14 July 2016

Maintenance: 300 mg PO 3 to 4 times daily; desired serum lithium level 0.6 to 1.2 mEq/L
Acute manic episode: 600 mg PO 3 times daily; desired serum lithium level 1 to 1.5 mEq/L

Safety/efficacy not established in children <12yo

Allergy to class/drug
Dehydration, cardiovascular disease, sodium depletion, concurrent diuretics, renal disease: needs inpatient monitoring if treatment required

Authors:

@@ Line 1: / Line 1: @@
-#REDIRECT[[Lithium toxicity]]
+==Administration==
+*Type:
+*Dosage Forms:
+*Routes of Administration: oral
+*Common Trade Names:
+==Adult Dosing==
+*Maintenance: 300 mg PO 3 to 4 times daily; desired serum lithium level 0.6 to 1.2 mEq/L
+*Acute manic episode: 600 mg PO 3 times daily; desired serum lithium level 1 to 1.5 mEq/L
+==Pediatric Dosing==
+''Safety/efficacy not established in children <12yo''
+==Special Populations==
+*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: D
+*[[Lactation risk categories|Lactation risk]]: infant risk cannot be ruled out
+===Renal Dosing===
+*Adult:
+*Pediatric:
+===Hepatic Dosing===
+*Adult:
+*Pediatric:
+==Contraindications==
+*Allergy to class/drug
+*Dehydration, cardiovascular disease, sodium depletion, concurrent diuretics, renal disease: needs inpatient monitoring if treatment required
+==Adverse Reactions==
+===Serious===
+*Toxicity (see [[Lithium toxicity]]
+*Seizure, ataxia, raised ICP
+*Angioedema
+*Erythema multiforme
+===Common===
+*Hypothroidism, weight gain
+*Nephrotoxicity
+*Fine tremor, hyperreflexia
+*Leukocytosis
+*Nausea, gastritis
+*Acne
+==Pharmacology==
+*Half-life: 14-50hr
+*Metabolism: Renal
+*Excretion: Renal
+==Mechanism of Action==
+==Comments==
+==See Also==
+*[[Lithium toxicity]]
+==References==
+<references/>
+[[Category:Pharmacology]]