Neonatal resuscitation: Difference between revisions

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''See [[3.5kg (newborn)|newborn critical care quick reference]] for vital signs and drug doses, and equipment sizes.''
''See [[3.5kg (newborn)|newborn critical care quick reference]] for vital signs and drug doses, and equipment sizes.''
==Background==
==Background==
*Neonate <1mo age


==Clinical Features==
==Clinical Features==
*Neonate in shock
*Neonate in shock
*Neonate <1mo age


==Differential Diagnosis==
==Differential Diagnosis==
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==Diagnosis==
==Diagnosis==
#Blood glucose (stat)
===Workup===
#Sepsis workup
*Blood glucose (stat)
#ECG
*[[Sepsis (peds)|Sepsis]] workup
#Ammonia to  rule in Inborn Errors^
*[[ECG]]
##Need to look up values for neonate. Ammonia is high as liver is immature (i.e. that's why neonates are jaundice)
*Ammonia to  rule in Inborn Errors^
**Need to look up values for neonate. Ammonia is high as liver is immature (i.e. that's why neonates are jaundice)


===Evaluation===
If hypoxic or evidence of CHF assume CHD
If hypoxic or evidence of CHF assume CHD
* CHF in neonate = hepatomegaly, wheezing, gallop
* CHF in neonate = hepatomegaly, wheezing, gallop
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** some use Pulse Ox <95%, less sensitive  
** some use Pulse Ox <95%, less sensitive  
*Abdominal xrays may help rule in intestinal disaster early
*Abdominal xrays may help rule in intestinal disaster early
{{Pediatric hypoglycemia chart}}


==Management==
==Management==
#Full [[sepsis]] work-up
*Full [[sepsis]] work-up
#*IV [[antibiotics]] and [[fluids]]
**IV [[antibiotics]] and [[fluids]]
#Pressors if CHD suspected
*Pressors if CHD suspected
#Intubate and give PGE
*[[Intubate]] and give [[PGE]]
#*Sides effects of PGE include apnea (10%)
**Sides effects of [[PGE]] include apnea (10%)
#If inborn errors suspected
*If inborn errors suspected
#*IV dextrose at 1.5 maintenance
**IV [[dextrose]] at 1.5 maintenance
#*Dialysis if ammonia >500
**Dialysis if ammonia >500
 


===Empiric Treatment for Unstable Neonates===
{{Empiric Treatment for Unstable Neonates))
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Medication/Intervention'''
| align="center" style="background:#f0f0f0;"|'''Indication'''
| align="center" style="background:#f0f0f0;"|'''Dose/Size (for neonate)'''
|-
| Glucose||[[Hypoglycemia]]||5–10 mL/kg of 10% dextrose in water IV
|-
| 3% normal saline||Symptomatic [[hyponatremia]]||3–5 mL/kg bolus IV
|-
| Calcium||[[Hypocalcemia]]||50–100 milligrams/kg calcium gluconate or 20 milligrams/kg calcium chloride IV
|-
| [[Cefotaxime]]||Infection||50 milligrams/kg IV
|-
| Ampicillin||Infection||50 milligrams/kg IV
|-
| Packed red blood cells||[[Anemia]]||10 mL/kg IV
|-
| Normal saline||Hypotension, dehydration||20 mL/kg IV
|-
| 10% dextrose in one fourth normal saline||Metabolic disease||1.5 maintenance (6 mL/kg/h for the first 10 kg)
|-
| Endotracheal intubation||Hypoventilation or frequent apnea||3mm for preemie; 3mm for term neonate, 4mm for older infant
|}


==See Also==
==See Also==

Revision as of 01:32, 9 May 2016

Use this note for the non-delivery related resuscitation of the newborn; see newborn resuscitation for immediate after-delivery resuscitation. See newborn critical care quick reference for vital signs and drug doses, and equipment sizes.

Background

  • Neonate <1mo age

Clinical Features

  • Neonate in shock

Differential Diagnosis

Sick Neonate

THE MISFITS [1]

Diagnosis

Workup

  • Blood glucose (stat)
  • Sepsis workup
  • ECG
  • Ammonia to rule in Inborn Errors^
    • Need to look up values for neonate. Ammonia is high as liver is immature (i.e. that's why neonates are jaundice)

Evaluation

If hypoxic or evidence of CHF assume CHD

  • CHF in neonate = hepatomegaly, wheezing, gallop
  • if unclear do Hyperoxia test
    • place infant on 100% O2 for 10 minutes
    • check ABG, if O2<100 torr, highly predictive of CHD
    • some use Pulse Ox <95%, less sensitive
  • Abdominal xrays may help rule in intestinal disaster early

Pediatric Hypoglycemia Dextrose Chart

Category Age Glucose Treatment Initial IV Bolus Maintenance Dose
Neonatal <2mo <40 D10W 2.5-5 mL/kg 6 mL/kg/h
Pediatric 2mo-8yrs <60 D25W 2 mL/kg

D10W:

  • 6 mL/kg/h for first 10 kg
  • + 3 mL/kg/h for 11–20 kg
  • + 1.5 mL/kg/h for each additional kg >20 kg
Adult >8yrs <70 D50W 50mL (1 amp) OR 1 mL/kg
  • Consider diluting the D25W or D50W bolus, with NS 1-to-1, as those concentrations may be sclerosing to veins
  • Recheck 5 minutes after dose and repeat dose if low.
  • Consider glucagon IM/SQ if IV access is not readily available

Management

{{Empiric Treatment for Unstable Neonates))

See Also

External Links

Video

{{#widget:YouTube|id=B6jEgEexbEU}}

References

  1. Brousseau T, Sharieff GQ. Newborn emergencies: the first 30 days of life. Pediatr Clin North Am. 2006 Feb;53(1):69-84, vi.