Traditional chinese medicine toxicology: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
==Background==
==Background==
*Traditional Chinese medicine has become increasingly popular in the US and other Western countries, and has remained extremely popular in China and Hong Kong.<ref name="Kam">Kam PC1, Liew S. Traditional Chinese herbal medicine and anaesthesia. Anaesthesia. 2002 Nov;57(11):1083-9.</ref>
*Although generally marketed as "natural" and "herbal" in nature, many contain contaminants in the form of heavy metals or conventional western medications.<ref name="Kam" />
**Studies have found, among others, cadmium, cobalt, copper, iron, manganese, nickel, lead, zinc, and mercury in traditional Chinese medicines<ref name="Kam" /><ref name="Chan">Chan K. Some aspects of toxic contaminants in herbal medicines. Chemosphere. 2003 Sep;52(9):1361-71.</ref>


 
==Common Toxic Herbs==
==Major Groups==
*Aconitine Group (most common)<ref name="Kam" />
* Aconitine Group
**Activates sodium channels → cardiac and neurotoxicity
**Cardiotoxicity (ventricular arrhythmia + hypotension)
**Paresthesias, N/V, arrhythmias, hypotension
*Podophyllin Group
*Podophyllin Group
**Neurotoxicity (convulsion + coma)
**Neurotoxicity (convulsion + coma)

Revision as of 05:34, 28 February 2016

Background

  • Traditional Chinese medicine has become increasingly popular in the US and other Western countries, and has remained extremely popular in China and Hong Kong.[1]
  • Although generally marketed as "natural" and "herbal" in nature, many contain contaminants in the form of heavy metals or conventional western medications.[1]
    • Studies have found, among others, cadmium, cobalt, copper, iron, manganese, nickel, lead, zinc, and mercury in traditional Chinese medicines[1][2]

Common Toxic Herbs

  • Aconitine Group (most common)[1]
    • Activates sodium channels → cardiac and neurotoxicity
    • Paresthesias, N/V, arrhythmias, hypotension
  • Podophyllin Group
    • Neurotoxicity (convulsion + coma)
  • Anticholinergic group
    • Tachy arrythmia + altered mental status
  • Digoxin-like agents
  • Other

See Also

References

  1. 1.0 1.1 1.2 1.3 Kam PC1, Liew S. Traditional Chinese herbal medicine and anaesthesia. Anaesthesia. 2002 Nov;57(11):1083-9.
  2. Chan K. Some aspects of toxic contaminants in herbal medicines. Chemosphere. 2003 Sep;52(9):1361-71.