Febrile nonhemolytic tranfusion reaction: Difference between revisions
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Revision as of 11:56, 7 February 2016
Background
- Occurs in 20% of patients due to recipient Ab against donor leukocytes
Clinical Features
- Fever, headache, myalgias, tachycardia, dyspnea, chest pain
Differential Diagnosis
Transfusion Reaction Types
- Acute
- Delayed
Acute allergic reaction
- Allergic reaction/urticaria
- Anaphylaxis
- Angioedema
- Anxiety attack
- Asthma exacerbation
- Carcinoid syndrome
- Cold urticaria
- Contrast induced allergic reaction
- Scombroid
- Shock
- Transfusion reaction
Diagnosis
Management
- Stop tranfusion pending rule-out of hemolytic transfusion reaction
- Give antipyretic
- Restart transfusion once hemolytic transfusion reaction is ruled-out