Prochlorperazine: Difference between revisions
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==Pediatric Dosing== | ==Pediatric Dosing== | ||
===2 yo and older, 9-14 kg=== | ===nausea/vomiting, severe=== | ||
====2 yo and older, 9-14 kg==== | |||
* 2.5 mg PO q12-24 h; Max 7.5 mg/day | * 2.5 mg PO q12-24 h; Max 7.5 mg/day | ||
===2 yo and older, 14-18 kg=== | ====2 yo and older, 14-18 kg==== | ||
* 2.5 mg PO q8-12 h; Max 10 mg/day | * 2.5 mg PO q8-12 h; Max 10 mg/day | ||
=== 2 yo and older, 18-39 kg=== | ==== 2 yo and older, 18-39 kg==== | ||
* 2.5 mg PO q8 hr; Max 15 mg/day | * 2.5 mg PO q8 hr; Max 15 mg/day | ||
=== 2 yo and older, >39 kg === | ==== 2 yo and older, >39 kg ==== | ||
* 5 mg PO q6-8 h, Max: 20 mg/day | * 5 mg PO q6-8 h, Max: 20 mg/day | ||
=== Schizophrenia=== | |||
==== 2-5 yo==== | |||
* 2.5 - 5 mg PO q6-8 hr, Max 20 mg/day | |||
====6-12 yo==== | |||
*2.5-5 mg PO q6-8 hr, Max 25 mg/day | |||
==Special Populations== | ==Special Populations== | ||
Revision as of 08:28, 5 February 2016
General
- Type: anti-psychotic and anti-emetic
- Dosage Forms: 5, 10
- Routes of Administration: IV, PO
- Common Trade Names: Compazine
Adult Dosing
Headache
- 10 mg IV (slow push or in 1L IV NS)
Nausea/Vomiting
- 5-10 mg PO or IV q6-8 hours
- Max: 40mg/day
Pediatric Dosing
nausea/vomiting, severe
2 yo and older, 9-14 kg
- 2.5 mg PO q12-24 h; Max 7.5 mg/day
2 yo and older, 14-18 kg
- 2.5 mg PO q8-12 h; Max 10 mg/day
2 yo and older, 18-39 kg
- 2.5 mg PO q8 hr; Max 15 mg/day
2 yo and older, >39 kg
- 5 mg PO q6-8 h, Max: 20 mg/day
Schizophrenia
2-5 yo
- 2.5 - 5 mg PO q6-8 hr, Max 20 mg/day
6-12 yo
- 2.5-5 mg PO q6-8 hr, Max 25 mg/day
Special Populations
- Pregnancy Rating: Pregnancy category C
- Lactation risk: Safety unknown
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: