Transfusion-associated circulatory overload: Difference between revisions
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*Frequently with rapid admin and large volume transfusions | *Frequently with rapid admin and large volume transfusions | ||
*Associated with a rapid rise in blood pressure, not hypotension | *Associated with a rapid rise in blood pressure, not hypotension | ||
{{TRALI vs TACO}} | |||
==Clinical Features== | ==Clinical Features== | ||
Revision as of 21:03, 4 February 2016
Background
- Often confused with TRALI
- Frequently with rapid admin and large volume transfusions
- Associated with a rapid rise in blood pressure, not hypotension
TRALI vs TACO
| TRALI | TACO | |
| Onset | Acute, within 6hrs | Often more gradual |
| BP | Low | High |
| Temp | Febrile | Normal |
| JVD/pedal edema | Unlikely | Likely |
| CVP/PAWP | Normal | Elevated |
| BNP | Normal | Elevated |
| Resp | Dyspneic | Dyspneic |
| CXR | B/l infiltrates | B/l infiltrates |
Clinical Features
- Dyspnea, orthopnea, peripheral edema, rapid rise in BP
Differential Diagnosis
Transfusion Reaction Types
- Acute
- Delayed
Acute allergic reaction
- Allergic reaction/urticaria
- Anaphylaxis
- Angioedema
- Anxiety attack
- Asthma exacerbation
- Carcinoid syndrome
- Cold urticaria
- Contrast induced allergic reaction
- Scombroid
- Shock
- Transfusion reaction
Diagnosis
- BNP or NT-proBNP to differentiate from other lung injury
Management
- O2,
- Supportive care
- Diuretics