Graft-vs-host disease: Difference between revisions
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Revision as of 13:52, 12 September 2015
Background
- Acute vs Chronic
- Acute: 1-12 weeks post graft
- Chronic: >12 weeks
- Transplanted graft with immunologically competent cells stimulated by host antigens and host is incapable of mounting an effective immunologic response
- Occurs in leukemia/lymphoma or immunocompromised
Clinical Features
Differential Diagnosis
Transfusion Reaction Types
- Acute
- Delayed
Diagnosis
- LFT abnormalities
- Pancytopenia
Management
- Glucocorticoids