Transplant complications: Difference between revisions
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**postoperative complications and complications of altered physiology secondary to the transplanted organ | **postoperative complications and complications of altered physiology secondary to the transplanted organ | ||
*Often transplant patients present with common medical problems but require unique management due to their altered physiology <ref>Tintinalli's</ref> | *Often transplant patients present with common medical problems but require unique management due to their altered physiology <ref>Tintinalli's</ref> | ||
==Epidemiology== | ==Epidemiology== | ||
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*Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant <ref>Tintinalli's</ref> | *Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant <ref>Tintinalli's</ref> | ||
< | <ref name="Tintinalli's"> | ||
Revision as of 18:55, 20 June 2015
Background
- Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines)
- First solid organ transplant was in 1954 (kidney)
- Most transplant patients require lifelong immunosuppression
- Types of emergencies
- transplant-related infection
- medication side effects
- rejection
- graft-versus-host disease
- postoperative complications and complications of altered physiology secondary to the transplanted organ
- Often transplant patients present with common medical problems but require unique management due to their altered physiology [1]
Epidemiology
- Types of presentations
- Infection (39%)
- Noninfectious GI/GU pathology (15%)
- Dehydration (15%)
- Electrolyte disturbances (10%)
- Cardiopulmonary pathology (10%)
- Injury (8%)
- Rejection (6%)
- Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant [2]
<ref name="Tintinalli's">