Ketofol: Difference between revisions

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*Mechanism of Action:
*Mechanism of Action:


==Administration==
==Preparation and Administration==
*Ketamine  
*'''[[Ketamine]]'''
**Comes in a 50 mg/mL concentration
**Comes in a 50 mg/mL concentration
**take a 10 mL saline flush and empty 2 mL and draw up 2 mL of ketamine  
**take a 10 mL saline flush and empty 2 mL and draw up 2 mL of ketamine  
***100 mg of ketamine in flush
***100 mg of ketamine in flush
*Propofol  
*'''[[Propofol]]'''
**Comes in a standard 10 mg/mL concentration.  
**Comes in a standard 10 mg/mL concentration.  
***fill a different 10 mL syringe with this you have 100 mg of propofol
***fill a different 10 mL syringe with this you have 100 mg of propofol

Revision as of 18:33, 18 June 2015

General

Adult Dosing

  • Starting dose: 0.5 mg/kg followed by another 0.5 mg/kg after 30-60 seconds
  • Maintenance: 0.25 mg/kg as needed

Pediatric Dosing

Special Populations

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

Preparation and Administration

  • Ketamine
    • Comes in a 50 mg/mL concentration
    • take a 10 mL saline flush and empty 2 mL and draw up 2 mL of ketamine
      • 100 mg of ketamine in flush
  • Propofol
    • Comes in a standard 10 mg/mL concentration.
      • fill a different 10 mL syringe with this you have 100 mg of propofol
  • If you mix the two in a new 20 or 30 mL syringe you get 100 mg ketamine + 100 mg propofol = 200 mg total.
    • Every one mL has 10 mg of ketofol

Comments

  • 2 definitions
    • 50% ketamine mixed with 50% propofol in same syringe
    • Pretreatment with 1/2 dose ketamine, followed by propofol

See Also

References