Mupirocin: Difference between revisions
ClaireLewis (talk | contribs) No edit summary |
(Replace manual dosing with dynamic SMW tables (Adult + Pediatric)) Tag: Reverted |
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==Adult Dosing== | ==Adult Dosing== | ||
===[[ | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Mupirocin]] [[Has Population::Adult]] | |||
|?Treats disease=Disease | |||
=== | |?Has Dose=Dose | ||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===[[ | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Mupirocin]] [[Has Population::Pediatric]] | |||
|?Treats disease=Disease | |||
=== | |?Has Dose=Dose | ||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Special Populations== | ==Special Populations== | ||
Revision as of 01:53, 20 March 2026
General
- Type: Antibiotic, Topical
- Dosage Forms: 2% cream, ointment
- Routes of Administration: topical
- Common Trade Names: Bactroban, Centany
Adult Dosing
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Balanoposthitis | cream BID | Antibacterial |
| Impetigo | 2% ointment q8hrs x 5 days | For nonbullous impetigo, topical antibiotics are as effective as oral antibiotics |
Pediatric Dosing
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Impetigo | 2% ointment applied TID x 5 days | Pediatric Topical |
Special Populations
- Pregnancy Rating: B
- Lactation risk: probably safe
Renal Dosing
- Adult: NA
- Pediatric: NA
Hepatic Dosing
- Adult: NA
- Pediatric: NA
Contraindications
- Allergy to class/drug
- large open wounds
- caution if renal impairment, mod-severe
Adverse Reactions
Serious
- hypersensitivity run
- anaphylaxis
- C. difficile-assoc diarrhea
- superinfection (prolonged use)
Common
- nausea
- burning
- headache
- pruritus
- pain
- stinging
Pharmacology
- Half-life: 20-40 min
- Metabolism: liver; CYP450; <0.3% systemic absorption
- Excretion: urine <3%
- Mechanism of Action: bacteriostatic or bactericidal, depending on susceptibility and concentration; reversibly binds to isoleucyl-tRNA synthetase, inhibiting protein synthesis (monoxycarbolic acid)
