ACTH (cosyntropin) stimulation test: Difference between revisions
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==Test== | ==Test== | ||
#Before: Draw serum cortisol | #Before: Draw serum cortisol | ||
#Time 0: ^0.25mg IM/IV over 2min | #Time 0: Give ^0.25mg IM/IV of ACTH (Cosyntropin) over 2min | ||
#Time 30: Draw serum cortisol | #Time 30: Draw serum cortisol | ||
#Time 60: Draw serum cortisol & give 100mg hydrodortison IVP | #Time 60: Draw serum cortisol & give 100mg hydrodortison IVP | ||
^0.125mg if | ^0.125mg if <2yrs old | ||
*Normal Response: Cortisol level doubles from baseline after Cosyntropin administration | *Normal Response: Cortisol level doubles from baseline after Cosyntropin administration | ||
*Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration | *Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration | ||
== Treatment == | == Treatment == | ||
Revision as of 22:42, 17 May 2015
Background
- ACTH (cosyntropin) stimulation test measures how well the adrenal glands respond to adrenocorticotropic hormone (ACTH)
- ACTH is a hormone produced in the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol
- Man-made form of ACTH is called cosyntropin
Test
- Before: Draw serum cortisol
- Time 0: Give ^0.25mg IM/IV of ACTH (Cosyntropin) over 2min
- Time 30: Draw serum cortisol
- Time 60: Draw serum cortisol & give 100mg hydrodortison IVP
^0.125mg if <2yrs old
- Normal Response: Cortisol level doubles from baseline after Cosyntropin administration
- Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration
Treatment
- Then give either
- Dexamethasone 6mg IV
- OR
- Hydrocortisone 100mg IV