Valacyclovir: Difference between revisions
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==General== | ==General== | ||
*Type: DNA polymerase | *Type: inhibits DNA polymerase | ||
*Dosage Forms: 500 | *Dosage Forms: 500, 1000 | ||
*Common Trade Names: Valtrex | *Common Trade Names: Valtrex | ||
| Line 7: | Line 7: | ||
===[[HSV-1]]=== | ===[[HSV-1]]=== | ||
* Acute episode: 2000 mg PO BID x 1 day | * Acute episode: 2000 mg PO BID x 1 day | ||
* Suppression: 500 mg PO | * Suppression: 500 mg PO Qday | ||
===Genital HSV=== | ===Genital HSV=== | ||
*1st episode: 1000 mg PO BID x 7-10 days, start within 48-72 hour of symptoms | *1st episode: 1000 mg PO BID x 7-10 days, start within 48-72 hour of symptoms | ||
* | * recurrence: 500 mg PO BID x 3 days, alternative: 1000 mg PO qday x 5 days | ||
=== | ===Shingles=== | ||
*1000 mg PO TID x 7 days | *1000 mg PO TID x 7 days | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===Genital HSV=== | ===Genital HSV=== | ||
* | *≥12 yrs same as adult dosing for adolescents | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | ||
*Lactation: | *Lactation: | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult | ||
**Pediatric | **Pediatric | ||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult | ||
**Pediatric | **Pediatric | ||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
===Common=== | ===Common=== | ||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: | ||
*Metabolism: | *Metabolism: | ||
*Excretion: | *Excretion: | ||
*Mechanism of Action: | *Mechanism of Action: | ||
==See Also== | ==See Also== | ||
Revision as of 15:32, 4 April 2015
General
- Type: inhibits DNA polymerase
- Dosage Forms: 500, 1000
- Common Trade Names: Valtrex
Adult Dosing
HSV-1
- Acute episode: 2000 mg PO BID x 1 day
- Suppression: 500 mg PO Qday
Genital HSV
- 1st episode: 1000 mg PO BID x 7-10 days, start within 48-72 hour of symptoms
- recurrence: 500 mg PO BID x 3 days, alternative: 1000 mg PO qday x 5 days
Shingles
- 1000 mg PO TID x 7 days
Pediatric Dosing
Genital HSV
- ≥12 yrs same as adult dosing for adolescents
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: