Polycythemia: Difference between revisions

Revision as of 17:39, 1 October 2019

Dependant on underlying etiology
May be entirely asymptomatic
Possible features include plethora, tendency towards thromboembolism or bleeding, splenomegaly, pruritus

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-#REDIRECT[[Polycythemia vera]]
+==Background==
+*AKA erythrocytosis
+*Refers to abnormally elevated Hb/Hct
+==Clinical Features==
+*Dependant on underlying etiology
+*May be entirely asymptomatic
+*Possible features include plethora, tendency towards [[thromboembolism]] or [[coagulopathy|bleeding]], splenomegaly, [[pruritus]]
+==Differential Diagnosis==
+*Primary polycythemia ([[myeloproliferative disorders]])
+**[[Polycythemia vera]]
+**[[Essential thrombocytosis (ET)]]
+**[[Chronic myelogenous leukemia]] (CML)
+**[[Leukemoid Reaction]]
+**[[Myelofibrosis]]
+*Secondary polycythemia (due to increased EPO)
+**Chronic [[hypoxemia]] (e.g. [[COPD]], physiologic [[altitude]] adaptations or [[chronic mountain sickness]])
+**Carboxyhemoglobin (chronic smokers)
+**Renal cyst or hydronephrosis
+**EPO-secreting tumors (RCC, [[hepatocellular carcinoma]]
+**Anabolic steroid abuse
+**Abnormal hemoglobins
+==Evaluation==
+*CBC
+**Hb >17.5 (males) or >15.5 (females)
+*Evaluate for underlying disease
+==Management==
+*Treat underlying pathology
+==Disposition==
+==See also==
+*[[Polycythemia vera]]
+*[[Myeloproliferative disorders]]
+==References==
+<references/>
+[[Category:Heme/Onc]]