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| ==Administration==
| | #REDIRECT[[Nitroglycerin]] |
| *Type: Vasodilator
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| *Dosage Forms: SL, IV
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| *Common Trade Names: Nitrostat
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| ==Adult Dosing==
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| ===Angina, acute===
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| *0.3 - 0.6mg SL q5min, max: 3 doses within 15 min
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| *IV form: 5 mcg/min IV, increase 5-20 mcg/min q3-5min.
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| ===[[Hypertension]]===
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| *5-200 mcg/min IV, start 5 mcg/min IV and increase increase 5 mcg/min q3-5min
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| ==Pediatric Dosing==
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| ===hypertension/CHF===
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| *1-5 mcg/kg/min IV
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| ==Special Populations==
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| *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
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| *[[Lactation risk categories|Lactation risk]]: safety unknown
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| ===Renal Dosing===
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| *Adult: not defined
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| *Pediatric: not defined
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| ===Hepatic Dosing===
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| *Adult: not defined
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| *Pediatric: not defined
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| ==Contraindications==
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| *Allergy to class/drug
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| *pericardial tamponade
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| *severe anemia
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| *SED use
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| ==Adverse Reactions==
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| ===Serious===
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| *[[hypotension]]
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| *[[bradycardia]]
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| *[[methemoglobinemia]]
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| ===Common===
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| *[[headache]]
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| *lightheadedness
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| *[[dizziness]]
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| *flushing
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| *reflex tachycardia
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| *edema
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| ==Pharmacology==
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| *Half-life: 1-3 min
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| *Metabolism: liver
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| *Excretion: urine
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| ==Mechanism of Action==
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| *Stimulates cGMP production, resulting in vascular smooth muscle relaxtion
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| ==Comments==
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| ==See Also==
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| *[[IV nitroglycerine alternatives]]
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| ==References==
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| <references/>
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| [[Category:Pharmacology]]
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