United States Antibiogram

Gram Positives

Category

Antibiotic

Strep. Group A, B, C, G

Strep. Pneumoniae

Viridans strep

Strep. anginosus gp

Enterococcus faecalis

Enterococcus faecium

MSSA

MRSA

CA-MRSA

Staph. Epidermidis

C. jeikeium

L. monocytogenes

Penicillins

Penicillin G

S

S

I

S

S

I

R

R

R

R

R

S

Penicillin V

S

S

I

S

S

I

R

R

R

R

R

R

Methicillin

S

S

I

S

R

R

S

R

R

S

R

R

Nafcillin/Oxacillin

S

S

I

S

R

R

S

R

R

S

R

R

Cloxacillin/Diclox.

S

S

I

S

R

R

S

R

R

S

R

R

Amino-Penicillins

AMP/Amox

S

S

I

S

S

I

R

R

R

R

R

S

Amox-Clav

S

S

I

S

S

S

S

R

R

R

R

X2

AMP-Sulb

S

S

I

S

S

S

S

R

R

R

R

S

Anti-Pseudomonal Penicillins

Ticarcillin

S

S

I

S

I

I

R

R

R

I

R

S

Ticar-Clav

S

S

I

S

I

I

S

R

R

I

R

X2

Pip-Tazo

S

S

I

S

S

I

S

R

R

S

X1

X2

Piperacillin

S

S

I

S

S

I

R

R

R

R

R

S

Carbapenems

Doripenem

S

S

S

S

I

R

S

R

R

S

X1

S

Ertapenem

S

S

S

S

R

R

S

R

R

S

R

I

Imipenem

S

S

S

S

S

I

S

R

R

S

R

S

Meropenem

S

S

S

S

I

R

S

R

R

S

X1

S

Aztreonam

R

R

R

R

R

R

R

R

R

R

R

R

Fluroquinolones

Ciprofloxacin

I

I

R

R

U

R

S

R

I

S

R

S

Ofloxacin

I

I

R

R

U

R

S

R

X1

S

R

R

Pefloxacin

R

R

X1

X1

R

R

S

R

X1

S

X1

R

Levofloxacin

S

S

S

S

S

R

S

R

I

S

X1

S

Moxifloxacin

S

S

S

S

S

I

S

I

I

S

X1

S

Gemifloxacin

S

S

S

S

S

I

S

I

I

S

X1

S

Gatifloxacin

S

S

S

S

S

I

S

I

I

S

X1

S

1st G Cephalo

Cefazolin

S

S

S

X1

R

X1

S

R

R

I

R

R

2nd G. Cephalo

Cefotetan

S

S

S

X1

R

X1

S

R

R

I

R

R

Cefoxitin

S

S

S

X1

R

X1

S

R

R

I

R

R

Cefuroxime

S

S

S

X1

R

X1

S

R

R

I

R

R

3rd/4th G. Cephalo

Cefotaxime

S

S

S

X1

R

X1

S

R

R

I

R

R

Cefizoxime

S

S

S

X1

R

X1

S

R

R

I

R

R

CefTRIAXone

S

S

S

X1

R

X1

S

R

R

I

R

R

Ceftaroline

S

S

S

X1

S

X1

S

S

S

S

X1

X1

CefTAZidime

S

S

I

X1

R

X1

I

R

R

I

R

R

Cefepime

S

S

S

X1

R

X1

S

R

R

I

R

Oral 1st G. Cephalo

Cefadroxil

S

S

S

X1

R

X1

S

R

R

I

R

R

Cephalexin

S

S

S

X1

R

X1

S

R

R

I

R

R

Oral 2nd G. Cephalo

Cefaclor/Loracarbef

S

S

S

X1

R

X1

S

R

R

I

R

R

Cefproxil

S

S

R

X1

R

X1

S

R

R

I

R

R

Cefuroxime axetil

S

S

S

X1

R

X1

S

R

R

I

R

R

Oral 3rd G. Cephalo

Cefixime

S

S

S

X1

R

X1

R

R

R

R

R

R

Ceftibuten

S

I

R

X1

R

X1

R

R

R

R

R

R

Cefpodox/Cefdinir/Cefditoren

S

S

S

X1

R

X1

S

R

R

I

X1

R

Aminoglycosides

Gentamicin

R

R

X1

X1

SS

SS

S

R

X1

I

R

SS

Tobramycin

R

R

X1

X1

SS

R

S

R

X1

I

R

SS

Amikacin

R

R

X1

X1

SS

R

S

R

X1

I

R

SS

Chloramphenicol

S

S

X1

X1

I

I

I

R

X1

R

R

S

Clindamycin

S

S

X1

X1

R

R

S

R

I

R

R

Macrolides

Erythromycin

I

I

X1

X1

R

R

I

R

I

I

R

S

Azithromycin

I

I

X1

X1

R

R

S

R

I

R

R

S

Clarithromycin

I

I

X1

X1

R

R

S

R

I

R

R

S

Ketolide

Telithromycin

S

S

X1

X1

I

R

S

R

I

R

R

S

Tetracyclines

Doxycycline

I

S

X1

X1

R

R

I

I

S

R

R

S

Minocycline

S

S

X1

X1

R

R

S

I

S

R

R

S

Glycylcycline

Tigecycline

S

S

X1

X1

S

S

S

S

S

S

S

S

Daptomycin

S

X4

X1

X1

S

S

S

S

S

S

S

I

Glyco/Lipoclycopeptides

Vancomycin

S

S

X1

X1

S

I

S

S

S

S

S

S

Teicoplanin

S

S

X1

X1

S

I

S

S

S

I

S

S

Telavancin

S

S

X1

X1

S

S

S

S

S

S

S

S

Fusidic Acid

I

I

X1

X1

S

S

S

S

S

S

X1

Trimethoprim

S

I

X1

X1

S

R

I

I

S

S

R

S

TMP-SMX

X3

S

X1

X1

X3

R

S

S

S

I

R

S

Urinary Agents

Nitrofurantoin

S

S

X1

X1

S

S

S

S

S

X1

R

X1

Fosfomycin

S

X1

X1

S

I

S

S

S

X1

X1

R

Other

Rifampin

S

S

X1

X1

I

R

S

S

S

S

S

S

Metronidazole

R

R

X1

X1

R

R

R

R

R

R

R

R

Quinupristin dalfoppristin

S

S

X1

X1

R

S

S

S

S

S

S

S

Linezolid

S

S

X1

X1

S

S

S

S

S

S

S

S

Colistimethate

R

R

X1

X1

R

R

R

R

R

R

R

R

Gram Negatives

Category	Antibiotic	N. gonorrhoeae
Penicillins	Penicillin G	0
	Penicillin V	0
Anti-Staphylocccal Penicillins	Methicillin	0
	Nafcillin/Oxacillin	0
	Dicloxacillin	0
Amino-Penicillins	AMP/Amox	0
	Amox-Clav	+
	AMP-Sulb	+
Anti-Pseudomonal Penicillins	Ticar-Clav	+
	Pip-Tazo	+
Carbapenems	Doripenem	+
	Ertapenem	+
	Imipenem	+
	Meropenem	+
Monobactam	Aztreonam	+
Fluroquinolones	Ciprofloxacin	+*
	Ofloxacin	+*
	Levofloxacin	+*
	Moxifloxacin	+*
	Gemifloxacin
	Gatifloxacin	+*
1st G Cephalo	Cefazolin	+
2nd G Cephalo	Cefotetan	+/-
	Cefoxitin	+/-
	Cefuroxime	+/-
3rd/4th G Cephalo	Cefotaxime	+/-
	Cefizoxime	+/-
	CefTRIAXone	+
	Ceftaroline	+
	CefTAZidime	+/-
	Cefepime	+
Oral 1st G Cephalo	Cefadroxil	0
	Cephalexin	0
Oral 2nd G Cephalo	Cefaclor	+/-
	Cefproxil	+/-
	Cefuroxime	+/-
Oral 3rd G Cephalo	Cefixime	+
	Ceftibuten	+/-
	Cefpodox/ Cefdinir/ Cefditoren	+
Aminoglycosides	Gentamicin	0
	Tobramycin	0
	Amikacin	0
	Chloramphenicol	+
	Clindamycin	0
Macrolides	Erythromycin	+/-
	Azithromycin	+/-
	Clarithromycin	+/-
Ketolide	Telithromycin	+
Tetracyclines	Doxycycline	+/-
	Minocycline	+/-
Glycylcycline	Tigecycline	+
Sulfonamides	TMP-SMX	+/-
Urinary Agents	Nitrofurantoin	+
	Fosfomycin	+
Other	Rifampin	+
	Metronidazole	0
	Quinupristin-dalfoppristin	+
	Linezolid
	Daptomycin	0
	Colistimethate	0
	Telavancin	0
	Vancomycin	0

Key

• S susceptible/sensitive (usually)
• I intermediate (variably susceptible/resistant)
• R resistant (or not effective clinically)
• S+ synergistic with cell wall antibiotics
• U sensitive for UTI only (non systemic infection)
• X1 no data
• X2 active in vitro, but not used clinically
• X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
• X4 active in vitro, but not clinically effective for strep pneumonia

See Also

• Antibiotics (Main)
• Microbiology (Main)
• Antibiograms (Main)