Ceftaroline fosamil: Difference between revisions
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==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*[[Anaphylaxis]] | |||
*[[Hypersensitivity Reaction]] | |||
*[[Clostridium difficile]] associated diarrhea | |||
*SUPERINFECTION | |||
*Hemolytic [[Anemia]] | |||
===Common=== | ===Common=== | ||
*[[Diarrhea]] | |||
*[[Nausea]] | |||
*[[Rash]] | |||
*[[Constipation]] | |||
*[[Vomiting]] | |||
*ALT, AST elevated | |||
*[[Hypokalemia]] | |||
*Phlebitis | |||
==Pharmacology== | ==Pharmacology== | ||
Revision as of 03:12, 17 May 2014
General
- Type: 5th Generation Cephalosporin
- Dosage Forms: IV
- Common Trade Names: Teflro
Adult Dosing
Community Acquired Pneumonia
- 600 mg IV q12h x5-7 days
Cellulitis
- 600 mg IV q12h x5-14 days
Renal Dosing
- CrCl 30-50: 400 mg q12h; CrCl 15-30: 300 mg q12h; ESRD/HD: 200 mg q12h
Hepatic Dosing
- No adjustment
Pediatric Dosing
- Currently no pediatric dosing for this drug.
Special Populations
- Pregnancy Rating:B
- Lactation: Safety Unknown
- Renal Dosing
- Adult: CrCl 30-50: 400 mg q12h; CrCl 15-30: 300 mg q12h; ESRD/HD: 200 mg q12h
- Pediatric: Drug not available for pediatrics
- Hepatic Dosing
- Adult: No Adjustment
- Pediatric: NA
Contraindications
- Allergy to class/drug (see also Cephalosporin Cross-reactivity)
- Caution if hypersensitive to beta-lactams
- Caution if recent antibiotic-associated colitis history
Adverse Reactions
Serious
- Anaphylaxis
- Hypersensitivity Reaction
- Clostridium difficile associated diarrhea
- SUPERINFECTION
- Hemolytic Anemia
Common
- Diarrhea
- Nausea
- Rash
- Constipation
- Vomiting
- ALT, AST elevated
- Hypokalemia
- Phlebitis
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: