Thyroid disease (main): Difference between revisions
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#Endemic goiter- if patient from area of low iodine intake | #Endemic goiter- if patient from area of low iodine intake | ||
#Free t3 & t4 determines thyroid state - not total plasma conc | #Free t3 & t4 determines thyroid state - not total plasma conc | ||
# | #T4→ T3 active & rt3 inactive | ||
#TRH | #TRH → TSH → T4 → T3 | ||
==Thyroid Studies and Etiologies== | ==Thyroid Studies and Etiologies== | ||
Revision as of 01:48, 9 February 2017
Background
- Spectrum of Disease
- Myxedema coma << hypothyroid < euthyroid > hyperthyroid >> thyroid storm
Other
- Cretinism - no congenital T3 or T4
- Parafollicular C cells make calcitonin to keep the bone in
- Endemic goiter- if patient from area of low iodine intake
- Free t3 & t4 determines thyroid state - not total plasma conc
- T4→ T3 active & rt3 inactive
- TRH → TSH → T4 → T3
Thyroid Studies and Etiologies
- Hyperthyroidism
- Subclinical hyperthyroidism
- T3 toxicosis
- Thyroiditis, T4 ingestion, hyperthyroidism of elderly or cormorbid illness
- Euthyroid sick syndrome, central hypothyroidism
- Subclinical hypothyroidism, recovery from euthyroid sick syndrome
- Primary hypothyroidism
- TSH producing pituitary adenoma
See Also
References
- Sharma AN, Levy DL; Thyroid and Adrenal Disorders; in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2014, (Ch) 128: p 1676-1693.
- Agus, MSD: Chapter 86 – Endocrine Emergencies, in Fleisher & Ludwig’s Textbook of Pediatric EM, 6th Ed., Lippincott Williams & Williams, 2010, p. 779-780