Brugada syndrome

Pathophysiology

• Genetically-linked Na-channelopathy
  • Incomplete RBBB with ST elevation in V1-V3
  • Increased risk of sudden cardiac death
    • ~10%/yr
  • Much more common in men (up to 9x)

ECG Criteria

• Note - ECG findings can be transient

• Type 1-Elevated ST segment (>2mm) descends w/ upward convexity to a TWI
• Type 2-Elevated ST segment (>1mm) descends toward baseline then rises again (saddleback) to upright T wave
• Type 3-Elevated ST segment (<1mm) descends toward baseline then rises again to upright T wave

Disposition

• Pts need an AICD

See Also

• STEMI
• ST Segment Elevation (DDX)

Source

• UpToDate