Necrotizing enterocolitis: Difference between revisions
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*Bacterial overgrowth in bowel, translocation of bacteria into bowel wall, subsequent bacterial endotoxin and gas production | *Bacterial overgrowth in bowel, translocation of bacteria into bowel wall, subsequent bacterial endotoxin and gas production | ||
== | ==Clinical Features== | ||
*Poor feeding, lethargy, abd distention/tenderness | *Poor feeding, lethargy, abd distention/tenderness | ||
*Sepsis, pneumoperitoneum | *Sepsis, pneumoperitoneum | ||
*Stool is +/- heme + | *Stool is +/- heme + | ||
==Differential Diagnosis== | |||
*[[Sepsis (peds)|Sepsis]] | |||
*[[Pneumonia (peds)|Pneumonia]] | |||
*malro/volvulus | |||
*feeding intolerance (exclusion) | |||
{{Pediatric abdominal pain DDX}} | |||
==Work-Up== | ==Work-Up== | ||
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**Pseudo-kidney sign - bowel wall with hyperechoic center and hypoechoic rim | **Pseudo-kidney sign - bowel wall with hyperechoic center and hypoechoic rim | ||
**Assess for gas bubbles in liver and portal veins | **Assess for gas bubbles in liver and portal veins | ||
==Treatment== | ==Treatment== | ||
Revision as of 11:49, 19 December 2015
Background
- Abreviation: NEC
- Intestinal necrosis in previously well infant
- Predominantly affects preemies; 10-15% occurs in full-term pts
- Bacterial overgrowth in bowel, translocation of bacteria into bowel wall, subsequent bacterial endotoxin and gas production
Clinical Features
- Poor feeding, lethargy, abd distention/tenderness
- Sepsis, pneumoperitoneum
- Stool is +/- heme +
Differential Diagnosis
Pediatric Abdominal Pain
0–3 Months Old
- Emergent
- Nonemergent
3 mo–3 y old
- Emergent
- Nonemergent
3 y old–adolescence
- Emergent
- Nonemergent
Work-Up
Labs
- CBC
- Chem
- Sepsis evaluation
- Coags
Imaging
- Cross-table lateral to detect free air
- Pneumatosis intestinalis, pneumobilia, pneumoperitoneum, sentinel loops, portal gas
Radiography
- Pneumatosis on XR is hallmark
- Get KUB in supine position and left lat decubitus
- US
- Pseudo-kidney sign - bowel wall with hyperechoic center and hypoechoic rim
- Assess for gas bubbles in liver and portal veins
Treatment
- NPO
- Aggressive IV hydration
- Amp/gent/clinda x 48 hrs
- Surgery consult
See Also
Source
Tintinalli
