Mebendazole: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
*100mg PO BID x 3 days | |||
===Indications by Disease=== | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Mebendazole]] [[Has Population::Adult]] | {{#ask: [[Has DrugName::Mebendazole]] [[Has Population::Adult]] | ||
|?Treats disease=Disease | |?Treats disease=Disease | ||
|?Has Dose=Dose | |?Has Dose=Dose | ||
|?Has Context=Context | |?Has Context=Context | ||
|format=table | |format=table | ||
|limit=50 | |limit=50 | ||
|mainlabel=- | |mainlabel=- | ||
|headers=show | |headers=show | ||
|sort=Treats disease | |sort=Treats disease | ||
}} | }} | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
≥2yo: 100mg PO BID x 3 days | |||
===Indications by Disease=== | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Mebendazole]] [[Has Population::Pediatric]] | {{#ask: [[Has DrugName::Mebendazole]] [[Has Population::Pediatric]] | ||
|?Treats disease=Disease | |?Treats disease=Disease | ||
|?Has Dose=Dose | |?Has Dose=Dose | ||
|?Has Context=Context | |?Has Context=Context | ||
|format=table | |format=table | ||
|limit=50 | |limit=50 | ||
|mainlabel=- | |mainlabel=- | ||
|headers=show | |headers=show | ||
|sort=Treats disease | |sort=Treats disease | ||
}} | }} | ||
Latest revision as of 02:39, 20 March 2026
Administration
- Type: Antiparasitic (used to treat nematodes)
- Dosage Forms: Tablet 100mg
- Routes of Administration: Oral
- Common Trade Names: Emverm
Adult Dosing
- 100mg PO BID x 3 days
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Enterobius | 100mg PO once then repeat in 2 weeks | Adult |
Pediatric Dosing
≥2yo: 100mg PO BID x 3 days
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Enterobius | 100mg PO once then repeat in 2 weeks | Pediatric 2 years or older |
Special Populations
- Pregnancy Rating: C
- Lactation risk: infant risk cannot be ruled out
- Renal dosing: no adjustment
- Hepatic impairment: may need dose reduction
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Agranulocytosis
- Hepatitis
- Seizure
- Angioedema
Common
- Abdominal pain, diarrhea
Pharmacology
- Half-life: 0.8-11.5h
- Metabolism: Hepatic
- Excretion: Fecal
Mechanism of Action
- Causes parasitic microtubules to degenerate, inhibiting glucose uptake and glycogen storage