Penicillins

Types (with Indications)

• Natural Penicillins (Penicillin G and Penicillin V
  • Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis
    • Penicillin plus clindamycin (to decrease toxin synthesis)
  • Meningococcus Meningitis
  • Syphilis (Primary, 2ndary, and latent syphilis < 1 year duration)
  • Actinomycosis
  • Anthrax
  • Clostridial infections
  • Listeria
  • Pasteurella
• Penicilinase-Resistant Penicillins
  • Nafcillin, oxacillin, dicloxacillin
    • Agents of 1st choice for treatment of S. aureus and S. epidermidis that are not methicillin-reistant
• Expanded-Spectrum Penicillins
  • Ampicillin, amoxicillin (+ clavulanate)
    • Upper Respiratory Infections (due to S. pyogenes, S. pneumoniae, H. influenzae)
      • Sinusitis
      • Otitis media
      • Acute exacerbation of chronic bronchitis
    • Listeria
• Antipseudomonal Penicillins
  • Piperacillin
    • Infection following burns
    • Neutropenia

See Also

• Antibiotics (Main)

Source

Goodman & Gilman's Pharmacology