Bisacodyl: Difference between revisions
(edited dosage forms, strengths, routes of administration, trade names) |
(added half life, metabolism and excretion) |
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*Abdominal discomfort/colic, diarrhea, proctitis (with suppository use) | *Abdominal discomfort/colic, diarrhea, proctitis (with suppository use) | ||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: 8 hr | ||
*Metabolism: | *Metabolism: Metabolized to BHPM in the colon | ||
*Excretion: | *Excretion: Urine and bile | ||
==Mechanism of Action== | ==Mechanism of Action== | ||
Revision as of 23:03, 11 October 2017
Administration
- Type: laxative
- Dosage Forms: tablet, enema, suppository
- Dosage Strengths: tablet: 5mg; enema: 10mg/30mL; suppository: 10mg
- Routes of Administration: PO, PR
- Common Trade Names: Dulcolax, Correctol, BisacEvac, Bisacolax, Codulax, Alophen, Feen A Mint, Fleet Stimulant Laxative, Laxit, Modane
Adult Dosing
- 5-30mg PO daily
- 10mg suppository daily
Pediatric Dosing
- 6-11 yrs: 5mg or rectally daily
Special Populations
- Pregnancy Rating: A
- Lactation risk: infant risk cannot be ruled out
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
- Appendicitis
- Bowel obstruction
- Gastroenteritis
Adverse Reactions
Serious
- Colonic atony
Common
- Abdominal discomfort/colic, diarrhea, proctitis (with suppository use)
Pharmacology
- Half-life: 8 hr
- Metabolism: Metabolized to BHPM in the colon
- Excretion: Urine and bile
Mechanism of Action
- Stimulates peristalsis via parasympathetic reflexes