Sulfadiazine: Difference between revisions
(Text replacement - "* " to "*") |
Bmurray990 (talk | contribs) |
||
| Line 1: | Line 1: | ||
==Administration== | ==Administration== | ||
*Type: [[Antibiotic]] | *Type: [[Antibiotic]] | ||
*Dosage Forms: | *Dosage Forms: Tablet, 500mg | ||
*Routes of Administration: Oral | *Routes of Administration: Oral | ||
*Common Trade Names: | *Common Trade Names: | ||
==Adult Dosing== | ==Adult Dosing== | ||
Revision as of 19:08, 26 January 2019
Administration
- Type: Antibiotic
- Dosage Forms: Tablet, 500mg
- Routes of Administration: Oral
- Common Trade Names:
Adult Dosing
- 2-4g PO daily in 1-4 doses
Pediatric Dosing
- >2mo: 75-150 mg/kg PO daily in 1-4 doses
Special Populations
- Pregnancy Rating: C
- Lactation risk: Infant risk has been demonstrated
- Renal dosing: use with caution
- Hepatic dosing: use with caution
Contraindications
- Allergy to class/drug
- Infants <2mo (except to treat congenital toxoplasmosis)
- Pregnant women at term
- Breastfeeding
Adverse Reactions
Serious
- SJS/TEN
- Agranulocytosis, hemolytic anemia, leukopenia, thrombocytopenia, aplastic anemia,
- Crystalluria
Common
- Rash
- Nausea/vomiting, diarrhea, abdominal pain
Pharmacology
- Half-life: 7-16.8h
- Metabolism: Hepatic
- Excretion: Mostly renal
Mechanism of Action
- Inhibits bacterial synthesis of folic acid