Caffeine: Difference between revisions
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==General== | ==General== | ||
*Type: | *Type: Stimulant, Respiratory Stimulant, Nonselective Phosphodiesterase Enzyme Inhibitor | ||
*Dosage Forms: PO | *Dosage Forms: tablets, capsules, lozenges, oral solution, injectable solution | ||
*Common Trade Names: NoDoz, Recharge, Vivarin, Diurex | *Dosage Strengths: tablets: 200 mg; capsules: 200 mg; lozenges: 75 mg; oral solution: 20 mg/mL; injectable solution: 20 mg/mL | ||
*Routes of Administration: PO, IV, IM | |||
*Common Trade Names: NoDoz, Recharge, Vivarin, Diurex, Cafcit | |||
{{Caffeine common dosages table}} | {{Caffeine common dosages table}} | ||
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==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: 5 hours | ||
*Metabolism: | *Metabolism: Liver CYP450 | ||
*Excretion: | *Excretion: Urine | ||
*Mechanism of Action: | *Mechanism of Action: Adenosine receptor antagonist | ||
==Mechanism of Action== | |||
*Methylxanthine structure that antagonizes [[adenosine]] receptors | |||
==See Also== | ==See Also== | ||
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==References== | ==References== | ||
<references/> | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:Toxicology]] | [[Category:Toxicology]] | ||
Latest revision as of 22:40, 11 February 2021
General
- Type: Stimulant, Respiratory Stimulant, Nonselective Phosphodiesterase Enzyme Inhibitor
- Dosage Forms: tablets, capsules, lozenges, oral solution, injectable solution
- Dosage Strengths: tablets: 200 mg; capsules: 200 mg; lozenges: 75 mg; oral solution: 20 mg/mL; injectable solution: 20 mg/mL
- Routes of Administration: PO, IV, IM
- Common Trade Names: NoDoz, Recharge, Vivarin, Diurex, Cafcit
Common Dosages by Type
| Type | Amount | Caffeine^ |
| Coffee, brewed | 1 cup | 100mg |
| Coffee, instant | 1 cup | 75mg |
| Tea | 1 cup | 50mg |
| Red Bull | 1 can | 80mg |
| Rockstar | 1 can | 160mg |
| Excedrin Migraine | 2 tabs | 130mg |
^Average caffeine content can vary[1][2]
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Pharmacology
- Half-life: 5 hours
- Metabolism: Liver CYP450
- Excretion: Urine
- Mechanism of Action: Adenosine receptor antagonist
Mechanism of Action
- Methylxanthine structure that antagonizes adenosine receptors
See Also
References
- ↑ Food Standards Agency (2001) Statement on the Reproductive Effects of Caffeine. London: Food Standards Agency.
- ↑ Juliano LM and Griffiths RR. Caffeine. In Lowinson, J.H., Ruiz, P., Millman, R.B., Langrod, J.G. (Eds.). Substance Abuse: A Comprehensive Textbook, Fourth Edition. 2005. PP. 403-421. Baltimore: Lippincott, Williams, & Wilkins.